Cyclopentyl chloroformate → HCID 118037312, compound

HRID 715592Notes

Reaction equation

HRID 715592 reaction equation
[NH2:1][CH:2]1[CH2:7][CH2:6][N:5]([C:8]([O:10][CH2:11][C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)=[O:9])[CH2:4][CH2:3]1.Cl[C:19]([O:21][CH:22]1[CH2:26][CH2:25][CH2:24][CH2:23]1)=[O:20]>>[CH:22]1([O:21][C:19]([NH:1][CH:2]2[CH2:3][CH2:4][N:5]([C:8]([O:10][CH2:11][C:12]3[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=3)=[O:9])[CH2:6][CH2:7]2)=[O:20])[CH2:26][CH2:25][CH2:24][CH2:23]1

Participants

3

Reactant 2

HCID 2735892Cyclopentyl chloroformateHCID 178466404-Amino-1-N-Cbz-piperidine

Product 1

HCID 118037312HCID 118037312, compound

Procedure

The title compound is prepared from benzyl 4-aminopiperidine-1-carboxylate and cyclopentyl chloroformate following a procedure analogous to that described for Intermediate 26 Step 1. LC (method 1): tR=1.06 min; Mass spectrum (ESI+): m/z=347 [M+H]+.

Sources & evidence

ORD record
ord-e416051515ab46c489141fa9077c439c
Source dataset
uspto-grants-2015_11
Patent number
US09187477B2

Reaction notes

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