HuagongsheHuagongshe Chemistry Print Report · For research reference only
BOC-D-alanine → N~2~-(tert-Butoxycarbonyl)-N-methoxy-N-methyl-D-alaninamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | BOC-D-alanine | HCID 637606 | — |
| Reactant | (S)-tert-Butyl (1-(methoxy(methyl)amino)-1-oxopropan-2-yl)carbamate | HCID 11806530 | — |
| Product | N~2~-(tert-Butoxycarbonyl)-N-methoxy-N-methyl-D-alaninamide | HCID 23537239 | 88% |
Reaction Steps
The title compound was prepared as (2S)-2-[(tert-butoxy)carbonylamino]-N-methoxy-N-methylpropanamide with boc-D-alanine (20 grams, 105.7 mmol) to give the title compound (21.7 g, 88%): ES-MS (m/z) 233.2 [M+1]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09187479B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-83fe5a6452a34424b253068e5e248148 |
| Source note | uspto-grants-2015_11 |