Methyl 4-aminobenzoate → HCID 86701934, compound

HRID 715760Notes

Reaction equation

[CH:1]1([CH2:6][C:7](Cl)=[O:8])[CH2:5]CC[CH2:2]1.[NH2:10][C:11]1[S:12][C:13]([C:16]([O:18]C)=[O:17])=[CH:14][N:15]=1.NC1C=CC(C(OC)=O)=CC=1>>[CH3:5][CH:1]([CH3:2])[CH2:6][C:7]([NH:10][C:11]1[S:12][C:13]([C:16]([OH:18])=[O:17])=[CH:14][N:15]=1)=[O:8]

Participants

Reactant 3

HCID 12082Methyl 4-aminobenzoate

HCID 238005Methyl 2-aminothiazole-5-carboxylate

HCID 3485182Cyclopentylacetyl chloride

Product 1

HCID 86701934HCID 86701934, compound

Procedure

The title compound was prepared as described in Example 52A, substituting 3-methylbutanoyl chloride for 2-cyclopentylacetyl chloride and methyl 2-aminothiazole-5-carboxylate for methyl 4-aminobenzoate.

Sources & evidence

ORD record: ord-b6943fc2dd894137a1295a876b1eb4c9
Source dataset: uspto-grants-2015_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09187472B2

Reaction notes

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