HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromophenyl isocyanate → 1-(4-Bromophenyl)-3-(imidazo[1,2-a]pyridin-7-ylmethyl)urea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromophenyl isocyanate | HCID 75609 | — |
| Reactant | Imidazo(1,2-a)pyridin-7-ylmethanamine | HCID 55289825 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 1-(4-Bromophenyl)-3-(imidazo[1,2-a]pyridin-7-ylmethyl)urea | HCID 86701958 | — |
Reaction Steps
To a solution of imidazo[1,2-a]pyridin-7-ylmethanamine (500 mg, 3.40 mmol) in dichloromethane (17 ml) at room temperature was added 1-bromo-4-isocyanatobenzene (680 mg, 3.40 mmol) as a single portion. The resulting suspension was stirred overnight and then filtered with dichloromethane washes to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09187472B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-ea5bfc00ceed43a19e2b66ab0024b79f |
| Source note | uspto-grants-2015_11 |