Sodium Hydroxide → HCID 66584098, compound

Participants

Reaction Conditions

Reaction Steps

3-Methyl-4(3,3,5-trimethylcyclohex-1-yl)butyl acetate (2.54 kg, 10.0 mols, purity: 97%) sodium hydroxide (420 g, 10.5 mols) and water (8400 ml) were mixed together and heated at 90-95° C. under stirring for 10-12 h. The reaction mixture was cooled to 35° C. The aqueous phase was separated from the organic phase. The organic phase was washed once with 5% w/w aqueous NaCl and twice with water. The crude product was fractionated under reduced pressure to provide 3-Methyl-4(3,3,5-trimethylcyclohex-1-yl) butan-1-ol (1.95 kg, yield: 92%; GC purity: 98% sum of the isomers).

Provenance & Evidence