(S,R)-1-(2-tert-butoxycarbonylamino-2-phenylacetyl)-pyrrolidine-2-carboxylic acid → Boc-gly-pro-OH

HRID 716525Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 716525
C([O:8][C:9]([C@@H:11]1[CH2:15][CH2:14][CH2:13][N:12]1[C:16](=[O:26])[CH2:17][NH:18][C:19]([O:21][C:22]([CH3:25])([CH3:24])[CH3:23])=[O:20])=[O:10])C1C=CC=CC=1.C(OC(N[C@H](C1C=CC=CC=1)C(N1CCC[C@H]1C(O)=O)=O)=O)(C)(C)C>>[C:22]([O:21][C:19]([NH:18][CH2:17][C:16]([N:12]1[CH2:13][CH2:14][CH2:15][C@H:11]1[C:9]([OH:10])=[O:8])=[O:26])=[O:20])([CH3:25])([CH3:23])[CH3:24]

Komponenten

3

Edukt 2

HCID 10089106(S,R)-1-(2-tert-butoxycarbonylamino-2-phenylacetyl)-pyrrolidine-2-carboxylic acidHCID 13152016N-Boc-glycyl-L-proline benzyl ester

Produkt 1

HCID 11673468Boc-gly-pro-OH

Versuchsvorschrift

Compound 27 was synthesized from compound 26, following the procedure as described for compound 3a, as a white solid. MS (ESI, EI−) m/z=271 (MH−).

Quellen und Nachweise

ORD-Eintrag
ord-89565b3c01b04765afe9794003d73017
Quelldatensatz
uspto-grants-2015_11
Patentnummer
US09187496B2

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