HuagongsheHuagongshe Chemistry Print Report · For research reference only
Proline benzyl ester hydrochloride → (S,R)-1-(2-ethoxycarbonylamino-2-phenylacetyl)-pyrrolidine-2-carboxylic acid benzyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Proline benzyl ester hydrochloride | HCID 2733413 | — |
| Reactant | (S,R)-1-(2-tert-butoxycarbonylamino-2-phenylacetyl)-pyrrolidine-2-carboxylic acid benzyl ester | HCID 15288611 | — |
| Reactant | (R)-ethoxycarbonylamino-phenyl-acetic acid | HCID 16116512 | — |
| Product | (S,R)-1-(2-ethoxycarbonylamino-2-phenylacetyl)-pyrrolidine-2-carboxylic acid benzyl ester | HCID 67241516 | — |
Reaction Steps
Compound 42 was synthesized from compound 41 (2 mmol) and L-proline benzyl ester hydrochloride (2.2 mmol), following the procedure as described for compound 2a.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09187496B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-36b1cc20fb864af6b9cef95df5147238 |
| Source note | uspto-grants-2015_11 |