Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
(E)-tert-butyl 3-(2-acetyl-5-chlorophenyl)acrylate → (E)-3-(2-acetyl-5-chlorophenyl)acrylic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | (E)-tert-butyl 3-(2-acetyl-5-chlorophenyl)acrylate | HCID 89499883 | — |
| 용매 | Trifluoroacetic acid methylene chloride | HCID 21863450 | — |
| 생성물 | (E)-3-(2-acetyl-5-chlorophenyl)acrylic acid | HCID 66744692 | 100% |
반응 단계
A solution of Intermediate 4A (0.048 g, 0.171 mmol) in 50% TFA/DCM (2 mL) was stirred at rt. After 1 h, the reaction was concentrated to give Intermediate 4 (0.038 g, 100%) as a yellow solid. The material was carried onto the next step without further purification. MS (ESI) m/z: 225.1 (M+H)+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09192607B2 |
| 출처 데이터셋 | uspto-grants-2015_11 |
| ORD ID | ord-24f99d9d79b84daf80ac186a81c2b0cf |
| 출처 메모 | uspto-grants-2015_11 |