N-carboxy-gamma-methyl-L-glutamic anhydride → HCID 89839269, compound

HRID 716643Notes

Reaction equation

HRID 716643 reaction equation
C([NH:4][C@H:5]([C:7]([O:9]C(=O)[C@H](C)NC(O)=O)=[O:8])[CH3:6])(O)=[O:2].C([NH:21][C@@H:22]1[C:28](=[O:29])[O:27][C:25](=[O:26])[CH:24]([CH3:30])[CH2:23]1)(O)=O>C1C=CC=CC=1>[CH3:6][C@H:5]([NH2:4])[C:7]([OH:9])=[O:8].[CH3:30][CH:24]([C:25]([OH:26])=[O:2])[CH2:23][C@@H:22]([C:28]([OH:27])=[O:29])[NH2:21]

Participants

4

Reactant 2

HCID 53678246N-carboxy-gamma-methyl-L-glutamic anhydrideHCID 87730064HCID 87730064, compound

Product 1

HCID 89839269HCID 89839269, compound

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

N-carboxy-L-alanine anhydride and N-carboxy-γ-methyl-L-glutamic acid anhydride were added to benzene at a molar ratio of 9:1 and 1.8 wt % in total, and the mixture was stirred at 55° C.-65° C. for 3-4 days to give a poly-L-alanine/γ-methyl-L-glutamic acid copolymer (molar ratio 9:1).

Sources & evidence

ORD record
ord-363d1159877e46d58e9c6de194932c4d
Source dataset
uspto-grants-2015_11
Patent number
US09192624B2

Reaction notes

Loading…