1-(4-Bromophenyl)propan-2-one → HCID 86691331, compound

HRID 716738Notes

Reaction equation

HRID 716738 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][C:9](=O)[CH3:10])=[CH:4][CH:3]=1.[CH:12]12[NH:19][CH:16]([CH2:17][CH2:18]1)[CH2:15][O:14][CH2:13]2>>[Br:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH:9]([N:19]2[CH:12]3[CH2:18][CH2:17][CH:16]2[CH2:15][O:14][CH2:13]3)[CH3:10])=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 7363321-(4-Bromophenyl)propan-2-oneHCID 152351793-Oxa-8-azabicyclo(3.2.1)octane

Product 1

HCID 86691331HCID 86691331, compoundYield 28.5%

Procedure

The title compound (54 mg, colorless oil) was prepared from 1-(4-bromophenyl)propan-2-one (130 mg) and 3-oxa-8-azabicyclo[3.2.1]octane (100 mg), as in Reference Example P-R5-1.

Sources & evidence

ORD record
ord-390d55b279054a6791d38a0800020002
Source dataset
uspto-grants-2015_11
Patent number
US09193695B2

Reaction notes

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