2,2-Diethyloxirane → 2-(3-(3-((2-Ethyl-2-hydroxybutyl)amino)phenyl)propyl)isoindoline-1,3-dione

HRID 716778Notes

Reaction equation

HRID 716778 reaction equation
[CH2:1]([C:3]1([CH2:6][CH3:7])[CH2:5][O:4]1)[CH3:2].[NH2:8][C:9]1[CH:10]=[C:11]([CH2:15][CH2:16][CH2:17][N:18]2[C:26](=[O:27])[C:25]3[C:20](=[CH:21][CH:22]=[CH:23][CH:24]=3)[C:19]2=[O:28])[CH:12]=[CH:13][CH:14]=1>>[CH2:1]([C:3]([OH:4])([CH2:6][CH3:7])[CH2:5][NH:8][C:9]1[CH:10]=[C:11]([CH2:15][CH2:16][CH2:17][N:18]2[C:26](=[O:27])[C:25]3[C:20](=[CH:21][CH:22]=[CH:23][CH:24]=3)[C:19]2=[O:28])[CH:12]=[CH:13][CH:14]=1)[CH3:2]

Participants

3

Reactant 2

HCID 2959712,2-DiethyloxiraneHCID 221249642-(3-(3-Aminophenyl)propyl)isoindoline-1,3-dione

Product 1

HCID 672964442-(3-(3-((2-Ethyl-2-hydroxybutyl)amino)phenyl)propyl)isoindoline-1,3-dione

Procedure

Reaction between 2,2-diethyloxirane and 2-(3-(3-aminophenyl)propyl)isoindoline-1,3-dione gives 2-(3-(3-((2-ethyl-2-hydroxybutyl)amino)phenyl)propyl)isoindoline-1,3-dione.

Sources & evidence

ORD record
ord-c9f70e117184416e94b5f981a25d171e
Source dataset
uspto-grants-2015_11
Patent number
US09193669B2

Reaction notes

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