1-Oxaspiro(2.4)heptane → 2-(3-(3-(((1-Hydroxycyclopentyl)methyl)amino)phenyl)propyl)isoindoline-1,3-dione

HRID 716779Notes

Reaction equation

HRID 716779 reaction equation
[O:1]1[C:3]2([CH2:7][CH2:6][CH2:5][CH2:4]2)[CH2:2]1.[NH2:8][C:9]1[CH:10]=[C:11]([CH2:15][CH2:16][CH2:17][N:18]2[C:26](=[O:27])[C:25]3[C:20](=[CH:21][CH:22]=[CH:23][CH:24]=3)[C:19]2=[O:28])[CH:12]=[CH:13][CH:14]=1>>[OH:1][C:3]1([CH2:2][NH:8][C:9]2[CH:10]=[C:11]([CH2:15][CH2:16][CH2:17][N:18]3[C:26](=[O:27])[C:25]4[C:20](=[CH:21][CH:22]=[CH:23][CH:24]=4)[C:19]3=[O:28])[CH:12]=[CH:13][CH:14]=2)[CH2:7][CH2:6][CH2:5][CH2:4]1

Participants

3

Reactant 2

HCID 6379911-Oxaspiro(2.4)heptaneHCID 221249642-(3-(3-Aminophenyl)propyl)isoindoline-1,3-dione

Product 1

HCID 672966882-(3-(3-(((1-Hydroxycyclopentyl)methyl)amino)phenyl)propyl)isoindoline-1,3-dione

Procedure

Reaction between 1-oxaspiro[2.4]heptane and 2-(3-(3-aminophenyl)propyl)isoindoline-1,3-dione gives 2-(3-(3-(((1-hydroxycyclopentyl)methyl)amino)phenyl)propyl)isoindoline-1,3-dione.

Sources & evidence

ORD record
ord-dc1e12c7bb654d5bb05a8f88411b1a20
Source dataset
uspto-grants-2015_11
Patent number
US09193669B2

Reaction notes

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