HCID 71090169, compound → HCID 86715698, compound

Participants

Reaction Steps

1,1-Dimethyl-6-(4-nitrophenoxy)-1,3-dihydro-2-benzofuran (Intermediate 69, 280 mg, 0.98 mmol) was dissolved in ethanol (5 ml), 5% w/w Pd/C was added and the reaction mixture was stirred for 4 hours under hydrogen atmosphere (2 bar). The catalyst was filtered off and the solvent evaporated to dryness to afford a pale yellow solid, which was purified by re-slurry in Et2O, to afford the title compound (80 mg) as off-white solid.

Provenance & Evidence