Trifluoroacetic acid → HCID 71113011, compound

Participants

Reaction Steps

A solution of 1,1-dimethylethyl((1R)-2-{[4-(1,3-dihydro-2-benzofuran-5-yloxy)phenyl]amino}-1-methyl-2-oxoethyl)carbamate (Intermediate 76, 130 mg, 0.326 mmol) and TFA (1 ml) in dichloromethane (4 ml) was stirred under argon at room temperature. The reaction mixture was stirred at room temperature for 1 hour. The mixture was concentrated and the residue was purified by SCX to afford the title compound (94 mg), which was directly used in the next step.

Provenance & Evidence