Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 717283Generated: October 26, 2026

Hydrochloric Acid → 4-Fluoro-2-(pyridin-4-yl)benzoic acid hydrochloride

https://huagongshe.com/reaction/717283

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantMethyl 4-fluoro-2-(pyridin-4-yl)benzoateHCID 46317422—
Product4-Fluoro-2-(pyridin-4-yl)benzoic acid hydrochlorideHCID 86680855—

Reaction Conditions

Temperature90 °C

Reaction Steps

A mixture of methyl 4-fluoro-2-(pyridin-4-yl)benzoate (0.88 g) and 6 N hydrochloric acid (13 mL) was stirred at 90° C. for 18 hr. The solvent was evaporated under reduced pressure to give the title compound (0.96 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09193709B2
Source datasetuspto-grants-2015_11
ORD IDord-602d608e21c34dec84fc8e95bcf7597a
Source noteuspto-grants-2015_11