Methanesulfonyl chloride → 76345-45-4

HRID 717319Notes

Reaction equation

HRID 717319 reaction equation
[CH3:1][S:2](Cl)(=[O:4])=[O:3].[N+:6]([C:9]1[CH:14]=[C:13]([NH2:15])[CH:12]=[CH:11][C:10]=1[NH2:16])([O-:8])=[O:7]>N1C=CC=CC=1>[NH2:16][C:10]1[CH:11]=[CH:12][C:13]([NH:15][S:2]([CH3:1])(=[O:4])=[O:3])=[CH:14][C:9]=1[N+:6]([O-:8])=[O:7]

Participants

4

Reactant 2

HCID 31297Methanesulfonyl chlorideHCID 43383702-Nitro-4-phenylenediamine

Product 1

HCID 1270965376345-45-4

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

Methanesulfonyl chloride (11.5 g, 0.1 mmol) was added gradually over 3 min to a solution of 2-nitrobenzene-1,4-diamine (15.3 g) in pyridine (70 ml). The temperature of the mixture rose to ca. 70° C. The solution was set aside for 10 min, and then refluxed for 15 min. The pyridine was evaporated under reduced pressure, and the residue was recrystallized from ethanol (with charcoal) to give the product as white solid.

Workup

  1. customrose to ca. 70° C
  2. temperaturerefluxed for 15 min
  3. customThe pyridine was evaporated under reduced pressure
  4. customthe residue was recrystallized from ethanol (with charcoal)

Sources & evidence

ORD record
ord-10eeb3b8175a404fbb739865ea5f53ab
Source dataset
uspto-grants-2015_11
Patent number
US09193717B2

Reaction notes

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