HuagongsheHuagongshe Chemistry Print Report · For research reference only
(4-Fluoro-2-nitro-phenyl)-carbamic acid tert-butyl ester → N1-(tert-Butoxycarbonyl)-4-fluoro-1,2-phenylenediamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (4-Fluoro-2-nitro-phenyl)-carbamic acid tert-butyl ester | HCID 59705030 | — |
| Catalyst | Zinc | HCID 23994 | — |
| Product | N1-(tert-Butoxycarbonyl)-4-fluoro-1,2-phenylenediamine | HCID 24688763 | — |
Reaction Steps
The title compound was prepared from the tert-butyl 4-fluoro-2-nitrophenylcarbamate (Example A6; 3 mmol) by reduction with zinc according to the general procedure B. Obtained as a yellow solid (66%), MS (EI) 227 [(M+1)+].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09193710B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-15297f284e624d0188838d8b07deadb7 |
| Source note | uspto-grants-2015_11 |