HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,1-Dimethylethyl N-(2-amino-4-chlorophenyl)carbamate → Tert-butyl 4-chloro-2-(3-oxo-3-(pyridazin-4-yl)propanamido)phenylcarbamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,1-Dimethylethyl N-(2-amino-4-chlorophenyl)carbamate | HCID 57456272 | — |
| Reactant | Tert-butyl 3-oxo-3-(pyridazin-4-yl)propanoate | HCID 71281628 | — |
| Product | Tert-butyl 4-chloro-2-(3-oxo-3-(pyridazin-4-yl)propanamido)phenylcarbamate | HCID 89421726 | — |
Reaction Steps
The title compound was prepared from the reaction of tert-butyl 2-amino-4-chlorophenylcarbamate (Example B5; 1 mmol) and tert-butyl 3-oxo-3-(pyridazin-4-yl)propanoate (Example C1; 1 mmol) according to the general procedure D. Obtained as a yellow solid (83%), MS (EI) 391 [(M+1)+].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09193710B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-4ce495dfeae44edd9a9fdd9c4e5709f8 |
| Source note | uspto-grants-2015_11 |