O-(2,4,6-Trimethylbenzenesulfonyl)hydroxylamine → 1,2-Diamino-4,5-difluoropyridinium 2,4,6-trimethylbenzenesulfonate

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Reaction Steps

2-[(Aminooxy)sulfonyl]-1,3,5-trimethylbenzene was added to a solution of 4,5-difluoropyridin-2-amine (47-3; 0.1 g, 0.000769 mol) in dichloromethane (10 mL). The reaction mixture was stirred for 20 min. A precipitate formed and it was filtered and dried under vacuum to afford the title compound. 1H NMR (400 MHz, DMSO) δ 8.91 (bs, 2H), 8.07-8.04 (m, 1H), 7.11-7.05 (m, 1H), 6.87 (s, 2H), 6.71 (s, 2H), 2.47 (s, 6H), 2.15 (s, 3H).

Provenance & Evidence