HRID717708

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CCCOc1ccc(-c2nc(-c3ccc4oc(C5(NC(=O)OC(C)(C)C)COC(C)(C)OC5)cc4c3)no2)cc1Cl

HCID66614932

未命名化合物

结构：COc1ccc2cc(-c3nc(-c4ccc5oc(C6(NC(=O)OC(C)(C)C)COC(C)(C)OC6)cc5c4)no3)oc2c1

HCID86660627

未命名化合物

PRODUCTS

生成物

结构：COc1ccc2cc(-c3nc(-c4ccc5oc(C(N)(CO)CO)cc5c4)no3)oc2c1

HCID46199993

未命名化合物

收率 26%

PROCEDURE

实验过程

When the product of Step F was substituted for tert-butyl 5-(5-(5-(3-chloro-4-propoxyphenyl)-1,2,4-oxadiazol-3-yl)benzofuran-2-yl)-2,2-dimethyl-1,3-dioxan-5-ylcarbamate in Example 36, Step E, the similar procedure afforded the title compound in 26% yield, as creamy green solid. 1H-NMR (CD3OD) 8.39 (d, 1H, J=1.74 Hz); 8.08 (dd, 1H, J=8.73, 1.89 Hz); 7.68 (b, 1H); 7.63 (d, 1H, J=8.73 Hz); 7.58 (d, 1H, J=8.7 Hz); 7.14 (d, 1H, J=1.8 Hz); 7.03 (s, 1H); 6.92 (dd, 1H, J=8.7, 2.22 Hz); 3.98 (d, 2H, J=11.00 Hz); 3.88 (d, 2H, J=11.01 Hz); 3.85 (s, 3H).