2-Bromoethyl methyl ether → HCID 58516003, compound

Participants

Reaction Steps

1-(8-Chloro-5-piperazin-1-ylimidazo[1,5-a]pyridine-6-yl)ethanone hydrochloride (16 mg, 0.052 mmol), N,N-diisopropylethylamine (27 μL, 0.16 mmol) and 1-bromo-2-methoxyethane (4.9 μL, 0.052 mmol) were stirred in acetonitrile (1.0 mL) for 22 hours at 65° C. Purification by preparative LCMS (pH 10) gave the desired compound (10 mg, 60%). LCMS calculated for C16H22ClN4O2 (M+H)+: m/z=337.1. found: 336.9.

Provenance & Evidence