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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 717913Generated: October 28, 2026

Methyl 4-aminobenzoate → HCID 7741301, compound

https://huagongshe.com/reaction/717913

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 4-aminobenzoateHCID 12082—
ReactantDiisopropylethylamineHCID 81531—
ReactantCyclopentylacetyl chlorideHCID 3485182—
SolventTetrahydrofuranHCID 8028—
ProductHCID 7741301HCID 7741301—

Reaction Steps

A solution of methyl 4-aminobenzoate (0.25 g, 1.654 mmol) in tetrahydrofuran (8.27 ml) was treated with diisopropylethylamine (0.433 ml, 2.481 mmol) and 2-cyclopentylacetyl chloride (0.279 g, 1.902 mmol) and the reaction mixture was stirred at ambient temperature for 2 hours. Concentration and normal phase chromatography provided the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09193723B2
Source datasetuspto-grants-2015_11
ORD IDord-097b999c3edb4258bc889d5e263f5da9
Source noteuspto-grants-2015_11