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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 717985Generated: October 29, 2026

4-Nitrobenzoic Acid → HCID 86702014, compound

https://huagongshe.com/reaction/717985

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Nitrobenzoic AcidHCID 6108—
ReactantIsoamylamineHCID 7894—
ReactantHCID 86701952HCID 86701952—
ProductHCID 86702014HCID 86702014—

Reaction Steps

The title compound was prepared as described in Example 1A, substituting (propan-2-yl)pyrrolidine for 3-methylbutan-1-amine and 4-(imidazo[1,2-a]pyridin-7-ylmethylcarbamoyl)benzoic acid for 4-nitrobenzoic acid. 1H NMR (400 MHz, DMSO-d6) δ ppm 9.44-9.36 (m, 1H), 8.86 (d, J=6.9 Hz, 1H), 8.31 (d, J=2.1 Hz, 1H), 8.14 (d, J=2.1 Hz, 1H), 8.01-7.95 (m, 2H), 7.80 (s, 1H), 7.65-7.59 (m, 2H), 7.49 (d, J=7.6 Hz, 1H), 4.69 (d, J=5.8 Hz, 2H), 4.15-4.05 (m, 1H), 3.47-3.19 (m, 2H), 2.39-2.26 (m, 1H), 1.96-1.57 (m, 4H), 0.93-0.85 (m, 6H); MS (ESI(+)) m/e 391 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09193723B2
Source datasetuspto-grants-2015_11
ORD IDord-d208d798866d40f5862b34a1c753515d
Source noteuspto-grants-2015_11