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4-Methylmorpholine → N'-(3,3-dimethylbutanoyl)-4-nitrobenzohydrazide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-Methylmorpholine | HCID 7972 | — |
| 反応物 | 3,3-Dimethylbutanoyl chloride | HCID 81514 | — |
| 反応物 | Benzoic acid, 4-nitro-, hydrazide | HCID 3693744 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | N'-(3,3-dimethylbutanoyl)-4-nitrobenzohydrazide | HCID 4628581 | — |
反応手順
A suspension of 4-nitrobenzohydrazide (0.500 g, 2.76 mmol), and 4-methylmorpholine (0.455 ml, 4.14 mmol) were stirred in dichloromethane (20 ml). 3,3-Dimethylbutanoyl chloride (0.422 ml, 3.04 mmol) was added and the reaction mixture was stirred for 2 hours. Normal phase chromatography of the crude reaction mixture gave the title compound.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09193723B2 |
| 出典データセット | uspto-grants-2015_11 |
| ORD ID | ord-9e83f9fe4bf64f14b526e16b525b28eb |
| 出典メモ | uspto-grants-2015_11 |