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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 718067Generated: October 31, 2026

HCID 67007739, compound → HCID 67007812, compound

https://huagongshe.com/reaction/718067

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 67007739HCID 67007739—
CatalystPalladiumHCID 23938—
SolventFormic AcidHCID 284—
SolventMethanolHCID 887—
ProductHCID 67007812HCID 67007812216.6%

Reaction Steps

Title compound 207 (0.32 g, 0.878 mmol) and Pd/C (0.093 g, 0.088 mmol) were combined in methanol (16.73 mL) and formic acid (0.836 mL). The reaction mixture was stirred at reflux for 2 h. The mixture was filtered and concentrated to afford title compound 208 (0.278 g, 99%) as a clear oil. LRMS: (calc) 246.14. (found) 247.3 (MH)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09193749B2
Source datasetuspto-grants-2015_11
ORD IDord-4e144e5ab42a4a28b5b145824ffc3768
Source noteuspto-grants-2015_11