Dimethylformamide → (Z)-4((5H-dibenzo[b,f]azepin-5-yl)methyl)benzoyl chloride

Participants

Reaction Steps

The title compound 390 (0.72 g, 2.2 mmol) and the oxalyl chloride (0.58 mL, 6.6 mmol) were mixed in DCM (10 mL) and few drops of DMF was added. The reaction mixture was stirred for 30 minutes and the solvent was evaporated (and stripped with toluene twice) to afford title compound 391 that was used crude for next step.

Provenance & Evidence