HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 718206Generated: October 29, 2026
(3R,4S,5R,6R)-3,4,5-Tris-trimethylsilanyloxy-6-trimethylsilanyloxymethyl-tetrahydro-pyran-2-on → delta-Gluconolactone
https://huagongshe.com/reaction/718206
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | (3R,4S,5R,6R)-3,4,5-Tris-trimethylsilanyloxy-6-trimethylsilanyloxymethyl-tetrahydro-pyran-2-on | HCID 10994280 | — |
| Solvent | Heptane | HCID 8900 | — |
| Product | delta-Gluconolactone | HCID 7027 | — |
Reaction Steps
A 10 L glass reactor was charged with (3R,4S,5R,6R)-3,4,5-tris(trimethylsilyloxy)-6-((trimethylsilyloxy)methyl)tetrahydro-2H-pyran-2-one (4.58 kg) and n-heptane (4.89 kg) and the mixture was cooled to −30 to −20° C. under nitrogen sparging for 30 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US09193751B2 |
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| Source dataset | uspto-grants-2015_11 |
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| ORD ID | ord-cd5b79de66294b5f927426f776d36dda |
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| Source note | uspto-grants-2015_11 |
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