p-Bromophenoxyacetic acid → 1-(4-(5-Amino-2-(4-methylphenethyl)thiazolo[5,4-d]pyrimidin-7-yl)piperazin-1-yl)-2-(4-bromophenoxy)ethanone

Participants

Role	Name	HCID	Charge
Reactant	p-Bromophenoxyacetic acid	HCID 74657	—
Reactant	2-(4-Methylphenethyl)-7-(piperazin-1-yl)thiazolo[5,4-d]pyrimidin-5-amine	HCID 66759053	—
Product	1-(4-(5-Amino-2-(4-methylphenethyl)thiazolo[5,4-d]pyrimidin-7-yl)piperazin-1-yl)-2-(4-bromophenoxy)ethanone	HCID 66758950	47%

Reaction Steps

This compound was prepared from 2-(4-methylphenethyl)-7-(piperazin-1-yl)thiazolo[5,4-d]pyrimidin-5-amine using 4-bromophenoxyacetic acid in a yield of 47%, according to the procedure for the synthesis of example 50.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US09193741B2
Source dataset	uspto-grants-2015_11
ORD ID	ord-1929171de71f4128a8c1c30cf6de2a34
Source note	uspto-grants-2015_11