Hexanoyl chloride → HCID 50942149, compound

HRID 718291Notes

Reaction equation

HRID 718291 reaction equation
[NH2:1][C:2]1[N:7]=[C:6]([N:8]2[CH2:13][CH2:12][N:11](C(OC(C)(C)C)=O)[CH2:10][CH2:9]2)[C:5]([NH2:21])=[C:4]([SH:22])[N:3]=1.[C:23](Cl)(=O)[CH2:24][CH2:25][CH2:26][CH2:27][CH3:28]>>[CH2:24]([C:23]1[S:22][C:4]2[N:3]=[C:2]([NH2:1])[N:7]=[C:6]([N:8]3[CH2:9][CH2:10][NH:11][CH2:12][CH2:13]3)[C:5]=2[N:21]=1)[CH2:25][CH2:26][CH2:27][CH3:28]

Participants

3

Reactant 2

HCID 67340Hexanoyl chlorideHCID 178452268HCID 178452268, compound

Product 1

HCID 50942149HCID 50942149, compoundYield 67%

Procedure

This compound was synthesized from tert-butyl 4-(2,5-diamino-6-mercaptopyrimidin-4-yl)piperazine-1-carboxylate using hexanoyl chloride, yielding the title compound in 67% yield.

Sources & evidence

ORD record
ord-95cc05062499443884b67b688920e51b
Source dataset
uspto-grants-2015_11
Patent number
US09193741B2

Reaction notes

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