(4-Chlorophenoxy)acetic acid → HCID 50942150, compound

HRID 718293Notes

Reaction equation

HRID 718293 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH2:9][CH2:10][C:11]2[S:12][C:13]3[N:14]=[C:15]([NH2:26])[N:16]=[C:17]([N:20]4[CH2:25][CH2:24][NH:23][CH2:22][CH2:21]4)[C:18]=3[N:19]=2)=[CH:4][CH:3]=1.[Cl:27][C:28]1[CH:38]=[CH:37][C:31]([O:32][CH2:33][C:34](O)=[O:35])=[CH:30][CH:29]=1>>[NH2:26][C:15]1[N:16]=[C:17]([N:20]2[CH2:21][CH2:22][N:23]([C:34](=[O:35])[CH2:33][O:32][C:31]3[CH:37]=[CH:38][C:28]([Cl:27])=[CH:29][CH:30]=3)[CH2:24][CH2:25]2)[C:18]2[N:19]=[C:11]([CH2:10][CH2:9][CH2:8][C:5]3[CH:6]=[CH:7][C:2]([F:1])=[CH:3][CH:4]=3)[S:12][C:13]=2[N:14]=1

Participants

3

Reactant 2

HCID 26229(4-Chlorophenoxy)acetic acidHCID 50942059HCID 50942059, compound

Product 1

HCID 50942150HCID 50942150, compoundYield 33%

Procedure

This compound was prepared from 2-(3-(4-fluorophenyl)propyl)-7-(piperazin-1-yl)thiazolo[5,4-d]pyrimidin-5-amine using 4-chlorophenoxyacetic acid in a yield of 33%, according to the procedure for the synthesis of example 50.

Workup

  1. customaccording to the procedure for the synthesis of example 50

Sources & evidence

ORD record
ord-46ee16311d294fcb8f8e026aaa126daf
Source dataset
uspto-grants-2015_11
Patent number
US09193741B2

Reaction notes

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