(4-Chlorophenoxy)acetic acid → HCID 50942151, compound

HRID 718294Notes

Reaction equation

HRID 718294 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH2:9][CH2:10][CH2:11][C:12]2[S:13][C:14]3[N:15]=[C:16]([NH2:27])[N:17]=[C:18]([N:21]4[CH2:26][CH2:25][NH:24][CH2:23][CH2:22]4)[C:19]=3[N:20]=2)=[CH:4][CH:3]=1.[Cl:28][C:29]1[CH:39]=[CH:38][C:32]([O:33][CH2:34][C:35](O)=[O:36])=[CH:31][CH:30]=1>>[NH2:27][C:16]1[N:17]=[C:18]([N:21]2[CH2:22][CH2:23][N:24]([C:35](=[O:36])[CH2:34][O:33][C:32]3[CH:38]=[CH:39][C:29]([Cl:28])=[CH:30][CH:31]=3)[CH2:25][CH2:26]2)[C:19]2[N:20]=[C:12]([CH2:11][CH2:10][CH2:9][CH2:8][C:5]3[CH:6]=[CH:7][C:2]([F:1])=[CH:3][CH:4]=3)[S:13][C:14]=2[N:15]=1

Participants

3

Reactant 2

HCID 26229(4-Chlorophenoxy)acetic acidHCID 509421472-(4-(4-Fluorophenyl)butyl)-7-(piperazin-1-yl)thiazolo[5,4-d]pyrimidin-5-amine

Product 1

HCID 50942151HCID 50942151, compoundYield 23%

Procedure

This compound was prepared from 2-(4-(4-fluorophenyl)butyl)-7-(piperazin-1-yl)thiazolo[5,4-d]pyrimidin-5-amine using 4-chlorophenoxyacetic acid in a yield of 23%, according to the procedure for the synthesis of example 50.

Workup

  1. customaccording to the procedure for the synthesis of example 50

Sources & evidence

ORD record
ord-e15f9e647a9b4faf924da6c760d1945f
Source dataset
uspto-grants-2015_11
Patent number
US09193741B2

Reaction notes

Loading…