4-Methoxyphenoxyacetic acid → HCID 66758710, compound

HRID 718296Notes

Reaction equation

HRID 718296 reaction equation
[N:1]1([C:7]2[C:8]3[N:16]=[C:15]([C:17]4[CH:22]=[CH:21][C:20]([CH3:23])=[CH:19][CH:18]=4)[S:14][C:9]=3[N:10]=[C:11]([NH2:13])[N:12]=2)[CH2:6][CH2:5][NH:4][CH2:3][CH2:2]1.[CH3:24][O:25][C:26]1[CH:36]=[CH:35][C:29]([O:30][CH2:31][C:32](O)=[O:33])=[CH:28][CH:27]=1>>[NH2:13][C:11]1[N:12]=[C:7]([N:1]2[CH2:2][CH2:3][N:4]([C:32](=[O:33])[CH2:31][O:30][C:29]3[CH:35]=[CH:36][C:26]([O:25][CH3:24])=[CH:27][CH:28]=3)[CH2:5][CH2:6]2)[C:8]2[N:16]=[C:15]([C:17]3[CH:22]=[CH:21][C:20]([CH3:23])=[CH:19][CH:18]=3)[S:14][C:9]=2[N:10]=1

Participants

3

Reactant 2

HCID 746494-Methoxyphenoxyacetic acidHCID 50942148HCID 50942148, compound

Product 1

HCID 66758710HCID 66758710, compoundYield 41%

Procedure

This compound was prepared from 7-(piperazin-1-yl)-2-p-tolylthiazolo[5,4-d]pyrimidin-5-amine using 4-methoxyphenoxyacetic acid in a yield of 41%, according to the procedure for the synthesis of example 50.

Workup

  1. customaccording to the procedure for the synthesis of example 50

Sources & evidence

ORD record
ord-154ec9c2360f46eaa1522469f2f76e23
Source dataset
uspto-grants-2015_11
Patent number
US09193741B2

Reaction notes

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