(4-Chlorophenoxy)acetic acid → HCID 50942246, compound

HRID 718297Notes

Reaction equation

HRID 718297 reaction equation
[N:1]1([C:7]2[C:8]3[N:16]=[C:15]([C:17]4[CH:22]=[CH:21][C:20]([CH3:23])=[CH:19][CH:18]=4)[S:14][C:9]=3[N:10]=[C:11]([NH2:13])[N:12]=2)[CH2:6][CH2:5][NH:4][CH2:3][CH2:2]1.[Cl:24][C:25]1[CH:35]=[CH:34][C:28]([O:29][CH2:30][C:31](O)=[O:32])=[CH:27][CH:26]=1>>[NH2:13][C:11]1[N:12]=[C:7]([N:1]2[CH2:2][CH2:3][N:4]([C:31](=[O:32])[CH2:30][O:29][C:28]3[CH:34]=[CH:35][C:25]([Cl:24])=[CH:26][CH:27]=3)[CH2:5][CH2:6]2)[C:8]2[N:16]=[C:15]([C:17]3[CH:22]=[CH:21][C:20]([CH3:23])=[CH:19][CH:18]=3)[S:14][C:9]=2[N:10]=1

Participants

3

Reactant 2

HCID 26229(4-Chlorophenoxy)acetic acidHCID 50942148HCID 50942148, compound

Product 1

HCID 50942246HCID 50942246, compoundYield 32%

Procedure

This compound was prepared from 7-(piperazin-1-yl)-2-p-tolylthiazolo[5,4-d]pyrimidin-5-amine using 4-chlorophenoxyacetic acid in a yield of 32%, according to the procedure for the synthesis of example 50.

Workup

  1. customaccording to the procedure for the synthesis of example 50

Sources & evidence

ORD record
ord-bbd68d5890e04e429f3491bfb05de7e2
Source dataset
uspto-grants-2015_11
Patent number
US09193741B2

Reaction notes

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