(4-Chlorophenoxy)acetic acid → HCID 50942152, compound

HRID 718298Notes

Reaction equation

HRID 718298 reaction equation
[CH2:1]([C:6]1[S:7][C:8]2[N:9]=[C:10]([NH2:21])[N:11]=[C:12]([N:15]3[CH2:20][CH2:19][NH:18][CH2:17][CH2:16]3)[C:13]=2[N:14]=1)[CH2:2][CH2:3][CH2:4][CH3:5].[Cl:22][C:23]1[CH:33]=[CH:32][C:26]([O:27][CH2:28][C:29](O)=[O:30])=[CH:25][CH:24]=1>>[NH2:21][C:10]1[N:11]=[C:12]([N:15]2[CH2:20][CH2:19][N:18]([C:29](=[O:30])[CH2:28][O:27][C:26]3[CH:32]=[CH:33][C:23]([Cl:22])=[CH:24][CH:25]=3)[CH2:17][CH2:16]2)[C:13]2[N:14]=[C:6]([CH2:1][CH2:2][CH2:3][CH2:4][CH3:5])[S:7][C:8]=2[N:9]=1

Participants

3

Procedure

This compound was prepared from 2-pentyl-7-(piperazin-1-yl)thiazolo[5,4-d]pyrimidin-5-amine using 4-chlorophenoxyacetic acid in a yield of 30%, according to the procedure for the synthesis of example 50.

Workup

  1. customaccording to the procedure for the synthesis of example 50

Sources & evidence

ORD record
ord-1f149cd735434e798f6e14dd1ec46e82
Source dataset
uspto-grants-2015_11
Patent number
US09193741B2

Reaction notes

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