(4-Chlorophenoxy)acetic acid → 1-(4-(2-(4-Fluorophenethyl)thiazolo[5,4-d]pyrimidin-7-yl)piperazin-1-yl)-2-(4-chlorophenoxy)ethanone

Participants

Role	Name	HCID	Charge
Reactant	(4-Chlorophenoxy)acetic acid	HCID 26229	—
Reactant	2-(4-Fluorophenethyl)-7-(piperazin-1-yl)thiazolo[5,4-d]pyrimidine	HCID 66758961	—
Product	1-(4-(2-(4-Fluorophenethyl)thiazolo[5,4-d]pyrimidin-7-yl)piperazin-1-yl)-2-(4-chlorophenoxy)ethanone	HCID 66758663	48%

Reaction Steps

This compound was prepared from 2-(4-fluorophenethyl)-7-(piperazin-1-yl)thiazolo[5,4-d]pyrimidine using 4-chlorophenoxyacetic acid in a yield of 48%, according to the procedure for the synthesis of example 50.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US09193741B2
Source dataset	uspto-grants-2015_11
ORD ID	ord-d71f48aed8c0469c8f876eed3cb3677b
Source note	uspto-grants-2015_11