HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lilial → HCID 86702777, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lilial | HCID 228987 | — |
| Reactant | (2-(P-Tolyl)ethyl)triphenylphosphonium bromide | HCID 20466351 | — |
| Reactant | Butyllithium | HCID 178418339 | — |
| Product | HCID 86702777 | HCID 86702777 | 42% |
Reaction Steps
Starting from p-methylphenethyltriphenylphosphonium bromide (5.04 g, 9.91 mmol, 1.0 equiv.), n-BuLi (1.6 M in hexanes, 6.2 mL, 9.91 mmol, 1.0 equiv.) and 3-(4-tert-butylphenyl)-2-methylpropanal (3.04 g, 14.9 mmol, 1.5 equiv.), 1.26 g (42%) of the title compound as a light yellow oil was obtained after purification by flash chromatography on SiO2 (cyclohexane/EtOAc 997:3).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09193935B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-9389887afbbb428a82bf740cd0d8d615 |
| Source note | uspto-grants-2015_11 |