4-Ethoxycarbonylphenylboronic acid → HCID 117732468, compound

HRID 718591Notes

Reaction equation

HRID 718591 reaction equation
Br[C:2]1[N:6]2[N:7]=[CH:8][CH:9]=[C:10]([N:11]3[CH2:16][CH2:15][O:14][CH2:13][CH2:12]3)[C:5]2=[N:4][C:3]=1[CH:17]1[CH2:20][N:19]([C:21]([O:23][C:24]([CH3:27])([CH3:26])[CH3:25])=[O:22])[CH2:18]1.[CH2:28]([O:30][C:31]([C:33]1[CH:38]=[CH:37][C:36](B(O)O)=[CH:35][CH:34]=1)=[O:32])[CH3:29]>>[CH2:28]([O:30][C:31]([C:33]1[CH:38]=[CH:37][C:36]([C:2]2[N:6]3[N:7]=[CH:8][CH:9]=[C:10]([N:11]4[CH2:16][CH2:15][O:14][CH2:13][CH2:12]4)[C:5]3=[N:4][C:3]=2[CH:17]2[CH2:20][N:19]([C:21]([O:23][C:24]([CH3:27])([CH3:26])[CH3:25])=[O:22])[CH2:18]2)=[CH:35][CH:34]=1)=[O:32])[CH3:29]

Participants

3

Reactant 2

HCID 27343504-Ethoxycarbonylphenylboronic acidHCID 117732467HCID 117732467, compound

Product 1

HCID 117732468HCID 117732468, compound

Procedure

Compound 19d was coupled with (4-(ethoxycarbonyl)phenyl)boronic acid under Suzuki reaction conditions as described in Example 1, Step E, to obtain compound 19e. Mass Spectrum (LCMS, ESI pos.): Calcd. for C28H34N4O5: 507.2 (M+H). found: 507.3.

Sources & evidence

ORD record
ord-1be9aeccf0e44632a63a69fb5b15ce2d
Source dataset
uspto-grants-2015_11
Patent number
US09193736B2

Reaction notes

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