Methanol → Methyl 2-(4-bromophenyl)acetate

Participants

Reaction Conditions

Reaction Steps

To a stirred solution of 2-(4-bromophenyl)acetic acid (10 g, 0046 mol) in MeOH (100 mL) was added sulfuryl dichloride (8.3 g, 0.069 mol) dropwise. The reaction mixture was stirred overnight at 80° C., allowed to cool to rt and concentrated under reduced pressure to afford compound 68a as a colorless oil. Mass Spectrum (GCMS, ESI pos.): Calcd. for C9H9BrO2: 228.0 (M). found: 228.0.

Provenance & Evidence