HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Bromopyridine → 6-Chloro-8-morpholino-3-(pyridin-3-yl)imidazo[1,2-b]pyridazine-2-carbaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Bromopyridine | HCID 12286 | — |
| Reactant | 6-Chloro-8-morpholinoimidazo[1,2-b]pyridazine-2-carbaldehyde | HCID 117728701 | — |
| Product | 6-Chloro-8-morpholino-3-(pyridin-3-yl)imidazo[1,2-b]pyridazine-2-carbaldehyde | HCID 117728322 | — |
Reaction Steps
Compound 73e was a coupled with 3-bromopyridine (0.100 mL, 1.25 mmol) according to the procedures described in Example 20, Step A to afford compound 73f. Mass Spectrum (LCMS, ESI pos.): Calcd. for C16H14ClN5O2: 344.0 (M+H). found: 344.0.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09193736B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-5042d48f647a49afbf3dd504a763b559 |
| Source note | uspto-grants-2015_11 |