Lithium hydroxide, monohydrate → (S)-2-(1-allyl-2-(1-phenylethylcarbamoyl)hydrazinyl)acetic acid

Participants

Reaction Steps

According to the procedure described in the synthesis method of Compound VI-2 with the modification that the reaction was carried out for 2 hours, (S)-ethyl 2-(1-allyl-2-(1-phenylethylcarbamoyl)hydrazinyl)acetate (Compound V-4) 183 mg (0.6 mmol) was reacted with lithium hydroxide monohydrate 30 mg (0.72 mmol) to obtain the title compound 157 mg (94%).

Provenance & Evidence