HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Benzothiophene-3-carbaldehyde → (S)-N-(benzo[b]thiophen-3-ylmethyl)-1,1-diethoxypropan-2-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Benzothiophene-3-carbaldehyde | HCID 227328 | — |
| Reactant | (2S)-1,1-Diethoxy-2-propanamine | HCID 12398111 | — |
| Product | (S)-N-(benzo[b]thiophen-3-ylmethyl)-1,1-diethoxypropan-2-amine | HCID 67088371 | 97% |
Reaction Steps
According to the procedure described in the synthesis method of Compound IX-2, (S)-1,1-diethoxypropan-2-amine (Compound XIX-1) 883 mg (6.0 mmol) was reacted with benzo[b]thiophene-3-carbaldehyde 827 mg (5.1 mmol) to obtain the title compound 1.45 g (97%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09193734B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-d490ff5aa1014b91b311bcb84fb1dc36 |
| Source note | uspto-grants-2015_11 |