2-(2-(Ethylcarbamoyl)-1-methylhydrazinyl)acetic acid → (S)-tert-butyl 4-(((S)-1,1-diethoxypropan-2-yl)(naphthalen-1-ylmethyl)amino)-3-(2-(2-(ethylcarbamoyl)-1-methylhydrazinyl)acetamido)-4-oxobutanoate

Participants

Reaction Steps

According to the procedure described in the synthesis method of Compound II-15, 2-(2-(ethylcarbamoyl)-1-methylhydrazinyl)acetic acid (Compound VI-9) 57 mg (0.33 mmol) was coupled with (S)-tert-butyl 3-amino-4-(((S)-1,1-diethoxypropan-2-yl)(naphthalen-1-ylmethyl)amino)-4-oxobutanoate (Compound IV-16) 100 mg (0.22 mmol) to obtain the title compound.

Provenance & Evidence