HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 53397539, compound → 1-(2-((S)-1-(((S)-1,1-diethoxypropan-2-yl)(naphthalen-1-ylmethyl)amino)-1,4-dioxo-4-(tritylamino)butan-2-ylamino)-2-oxoethyl)-1-methyl-4-(naphthalen-1-ylmethyl)semicarbazide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 53397539 | HCID 53397539 | — |
| Reactant | (S)-2-amino-N1-((S)-1,1-diethoxypropan-2-yl)-N1-(naphthalen-1-ylmethyl)-N4-tritylsuccinamide | HCID 67075487 | — |
| Product | 1-(2-((S)-1-(((S)-1,1-diethoxypropan-2-yl)(naphthalen-1-ylmethyl)amino)-1,4-dioxo-4-(tritylamino)butan-2-ylamino)-2-oxoethyl)-1-methyl-4-(naphthalen-1-ylmethyl)semicarbazide | HCID 86652585 | — |
Reaction Steps
According to the procedure described in the synthesis method of Compound II-15, 2-(1-methyl-2-(naphthalen-1-ylmethylcarbamoyl)hydrazinyl)acetic acid (Compound VI-8) 67 mg (0.23 mmol) was coupled with (S)-2-amino-N1—((S)-1,1-diethoxypropan-2-yl)-N1-(naphthalen-1-ylmethyl)-N4-tritylsuccinamide (Compound IV-19) 100 mg (0.16 mmol) to obtain the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09193734B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-1bc50313fa9e4a719aa45c0570079662 |
| Source note | uspto-grants-2015_11 |