HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 53397489, compound → 4-benzyl-1-(2-((S)-1-(((S)-1,1-diethoxypropan-2-yl)(quinolin-8-ylmethyl)amino)-1-oxopropan-2-ylamino)-2-oxoethyl)-1-methylsemicarbazide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 53397489 | HCID 53397489 | — |
| Reactant | (S)-2-amino-N-((S)-1,1-diethoxypropan-2-yl)-N-(quinolin-8-ylmethyl)propanamide | HCID 67075480 | — |
| Product | 4-benzyl-1-(2-((S)-1-(((S)-1,1-diethoxypropan-2-yl)(quinolin-8-ylmethyl)amino)-1-oxopropan-2-ylamino)-2-oxoethyl)-1-methylsemicarbazide | HCID 67075485 | — |
Reaction Steps
According to the procedure described in the synthesis method of Compound II-15, 2-(2-(benzylcarbamoyl)-1-methylhydrazinyl)acetic acid (Compound VI-3) 99 mg (0.42 mmol) was coupled with (S)-2-amino-N—((S)-1,1-diethoxypropan-2-yl)-N-(quinolin-8-ylmethyl)propanamide (Compound IV-11) 100 mg (0.28 mmol) to obtain the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09193734B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-3c3d331733254f629142c1bdf6a7f56f |
| Source note | uspto-grants-2015_11 |