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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 719009Generated: October 25, 2026

2-((3-(Pyridin-4-ylmethyl)ureido)oxy)acetic acid → HCID 86652606, compound

https://huagongshe.com/reaction/719009

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-((3-(Pyridin-4-ylmethyl)ureido)oxy)acetic acidHCID 53397519—
Reactant(S)-2-amino-3-(4-tert-butoxyphenyl)-N-((S)-1,1-diethoxypropan-2-yl)-N-(quinolin-8-ylmethyl)propanamideHCID 67075208—
ProductHCID 86652606HCID 86652606—

Reaction Steps

According to the procedure described in the synthesis method of Compound II-15, 2-(3-(pyridin-4-ylmethyl)ureidooxy)acetic acid (Compound VI-10) 67 mg (0.30 mmol) was coupled with (S)-2-amino-3-(4-tert-butoxyphenyl)-N—((S)-1,1-diethoxypropan-2-yl)-N-(quinolin-8-ylmethyl)propanamide (Compound IV-3) 100 mg (0.20 mmol) to obtain the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09193734B2
Source datasetuspto-grants-2015_11
ORD IDord-c5e5ea149e284358a99436ba71c629b6
Source noteuspto-grants-2015_11