HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(3-Ethylureidooxy)acetic acid → HCID 86652623, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(3-Ethylureidooxy)acetic acid | HCID 53397416 | — |
| Reactant | (S)-2-amino-N1-(benzo[b]thiophen-3-ylmethyl)-N1-((S)-1,1-diethoxy-propan-2-yl)-N4-tritylsuccinamide | HCID 67075021 | — |
| Product | HCID 86652623 | HCID 86652623 | — |
Reaction Steps
According to the procedure described in the synthesis method of Compound II-15, 2-(3-ethylureidooxy)acetic acid (Compound VI-13) 37 mg (0.23 mmol) was coupled with (S)-2-amino-N1-(benzo[b]thiophen-3-ylmethyl)-N1—((S)-1,1-diethoxypropan-2-yl)-N4-tritylsuccinamide (Compound IV-21) 100 mg (0.15 mmol) to obtain the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09193734B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-029f0ec3843542edacf1998c65715e0e |
| Source note | uspto-grants-2015_11 |