1-Bromo-2-methylpropane → HCID 14716165, compound

HRID 719079Notes

Reaction equation

HRID 719079 reaction equation
[CH3:1][C:2]([CH3:10])([CH:5]([OH:9])[CH:6]([CH3:8])[CH3:7])[CH2:3][OH:4].[CH2:11](Br)[CH:12]([CH3:14])[CH3:13]>>[CH3:11][CH:12]([CH3:14])[CH2:13][O:4][CH2:3][C:2]([CH3:10])([CH3:1])[CH:5]([OH:9])[CH:6]([CH3:8])[CH3:7]

Participants

3

Reactant 2

HCID 65551-Bromo-2-methylpropaneHCID 89462,2,4-Trimethyl-1,3-pentanediol

Product 1

HCID 14716165HCID 14716165, compoundYield 88%

Procedure

Treatment of 2,2,4-trimethylpentan-1,3-diol with isobutyl bromide employing the alkylation reaction conditions described above provided 1-(2-methylpropyloxy)-2,2,4-trimethylpentan-3-ol in 88.0% yield (355.5 g, b.p.=81–82 C./2.5 mmHg).

Sources & evidence

ORD record
ord-07659df43e924ec8bbdf5a523c1f2fa1
Source dataset
uspto-grants-2006_11
Patent number
US07132391B2

Reaction notes

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