2,2,4-Trimethyl-1,3-pentanediol → HCID 21896530, compound

HRID 719080Notes

Reaction equation

HRID 719080 reaction equation
[CH3:1][C:2]([CH3:10])([CH:5]([OH:9])[CH:6]([CH3:8])[CH3:7])[CH2:3][OH:4].[CH2:11](Cl)[CH:12]=[C:13]([CH3:15])[CH3:14]>>[CH3:14][C:13]([CH3:15])=[CH:12][CH2:11][O:4][CH2:3][C:2]([CH3:10])([CH3:1])[CH:5]([OH:9])[CH:6]([CH3:8])[CH3:7]

Participants

3

Reactant 2

HCID 89462,2,4-Trimethyl-1,3-pentanediolHCID 104291-Chloro-3-methyl-2-butene

Product 1

HCID 21896530HCID 21896530, compoundYield 92%

Procedure

Treatment of 2,2,4-trimethylpentan-1,3-diol with prenyl chloride employing the alkylation reaction conditions described above provided 1-(3-methyl-2-butenyloxy)-2,2,4-trimethylpentan-3-ol in 92.0% yield (393.8 g, b.p.=82–84 C./0.8 mmHg).

Sources & evidence

ORD record
ord-fc90dcaa79f548298fe76ba67b91ec5b
Source dataset
uspto-grants-2006_11
Patent number
US07132391B2

Reaction notes

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