HuagongsheHuagongshe Chemistry Print Report · For research reference only
[5-(4-Chloro-phenyl)-4-cyclopentylmethyl-2-(2-ethoxy-4-methoxy-phenyl)-4,5-dihydro-imidazol-1-yl]-(4-methyl-piperazin-1-yl)-methanone → HCID 11385877, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | [5-(4-Chloro-phenyl)-4-cyclopentylmethyl-2-(2-ethoxy-4-methoxy-phenyl)-4,5-dihydro-imidazol-1-yl]-(4-methyl-piperazin-1-yl)-methanone | HCID 11193096 | — |
| Reactant | HCID 178467020 | HCID 178467020 | — |
| Product | HCID 11385877 | HCID 11385877 | — |
Reaction Steps
4-[5-(4-Chloro-phenyl)-2-(2-ethoxy-4-methoxy-phenyl)-4-methyl-4,5-dihydro-imidazole-1-carbonyl]-piperazin-2-one was prepared from 5-(4-chloro-phenyl)-2-(2-ethoxy-4-methoxy-phenyl)-4-methyl-4,5-dihydro-1H-imidazole, trifluoroacetate salt (Example 17) in an analogous manner as described for the preparation of [5-(4-chloro-phenyl)-4-cyclopentylmethyl-2-(2-ethoxy-4-methoxy-phenyl)-4,5-dihydro-imidazol-1-yl]-(4-methyl-piperazin-1-yl)-methanone (Example 24). HR-MS (ES, m/z) observed 471.1801, calculated for C24H28N4O4Cl [(M+H)+]471.1794.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07132421B2 |
| Source dataset | uspto-grants-2006_11 |
| ORD ID | ord-5fcb905f9b904598a2dec2fc3cac7faa |
| Source note | uspto-grants-2006_11 |