HuagongsheHuagongshe Chemistry Print Report · For research reference only
Selenium Dioxide → 5-Bromonaphthalene-1,2-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Selenium Dioxide | HCID 24007 | — |
| Reactant | 2-Bromobenzyl bromide | HCID 76965 | — |
| Reactant | 5-Bromo-1,2,3,4-tetrahydronaphthalen-1-one | HCID 10889572 | — |
| Product | 5-Bromonaphthalene-1,2-dione | HCID 188016 | — |
Reaction Steps
2-Bromobenzyl bromide was converted into 5-bromotetralone according to the literature (J. Org. Chem. 1984, p4226). Treatment of 5-bromotetralone with selenium dioxide as described in Referene Example 1A yielded 5-bromo-[1,2]naphthoquinone, which was coupled with 2,3-diamino-benzoic acid, diacetate salt, as described in Reference Example 1A to yield the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07132419B2 |
| Source dataset | uspto-grants-2006_11 |
| ORD ID | ord-c6dac7f066b447849c3d94a1679e02dc |
| Source note | uspto-grants-2006_11 |